We live in a time of great uncertainty. Humanity is facing ever-increasing risks that threaten our future, including wars between major powers and even nuclear wars, natural and man-made pandemics, threats from advanced artificial intelligence (AI), and risks from new military technologies. These global catastrophic risks have the potential to kill billions of people and put the future of humanity at risk.
Together, we—scientists, policymakers, the public, and others—can work to address and reduce these risks. History offers some examples of successful collaboration. During the Cold War, global leaders cooperated to reduce stockpiles of weapons of mass destruction. Around the year 2000, scientists initiated a groundbreaking effort to minimize the threat of asteroid and comet impacts by improving tracking and calculations. Today, in the aftermath of COVID-19, a growing global movement is focusing on increasing preparedness and implementing measures to reduce the likelihood of future pandemics.
In 2025, AIs will be able to synthesise toxic molecules, scramble the results of their own evaluations and replicate themselves autonomously [1]. The Centre pour la Sécurité de l’AI is a French non-profit research organisation that raises awareness of the risks arising from AI systems and advocates technically informed regulation. Their mission is to reduce present and future risks, whether systemic, due to misuse, or arising from the currently opaque operation of generative AI.
HOW IS THE MONEY USED?
CeSIA funds three types of mission:
IMPACT ASSESSMENT
We draw on the expertise of LongView Philanthropy. In addition, CeSIA is eligible for tax relief in France, offering the possibility of tripling its impact.
Our Safeguarding the Future Fund tackles a difficult mission in an ever-changing landscape of threats. If you believe that reducing existential risks is essential to ensure the survival and prosperity of present and future generations, this fund is an extremely effective way to contribute.
HOW IS THE MONEY USED?
The money in this fund goes to the most promising initiatives to reduce the existential risks to humanity. It focuses on both immediate threats (likely to affect people living today) and long-term threats.
IMPACT ASSESSMENT
Effektiv Spenden allocates the donations made to its fund every six months. To do this, it draws on the expertise of external partners such as Longview Philanthropy and Founders Pledge’s Global Catastrophic Risks (GCR) fund.
[1]
Synthesizing toxic molecules : Dual use of artificial-intelligence-powered drug discovery, Urbina et al. 2022, in Nature Machine Intelligence
Tempering with evaluation results : Apollo Research, Frontier models are capable of in-context scheming, Meinke et al. 2024, Paragraphe 3.4, Models sometimes scheme without any goal nudging, Anthropic, Alignment Faking in Large Language Model, Greenblat, Denison et al. 2024
Autonomous replication : Frontier AI systems have surpassed the self-replicating red line, Xudong Pan, et al. 2024, Université de Fudan
Tax deductions in France are currently only available for donations to four of our recommended charities: Against Malaria Foundation, Good Food Institute, Helen Keller International, and Centre pour la Sécurité de l’IA
If you are taxable in France, you will benefit from a tax reduction of 66% of the amount of your donation up to the limit of the tax due or 20% of your taxable income.
In practice, this means that if you were planning to donate €100, you can triple this amount to reach a donation of €300 that you will declare, with a real cost of only €102 after tax reduction. This allows you to multiply the impact of your donation without increasing your planned expenditure.
You can read our full article on tax relief in France for more information.
We are able to offer tax deductibility for this association and all the organisations we recommend through our partners, Effektiv Spenden. If your tax residence is in Switzerland, please make your donations via this link, so that you can receive your tax receipt at the end of the tax year.
We work with partners around the world and can offer tax deductibility in many countries. Please contact us if you would like to make a donation from another country and we will discuss the tax options available to you. If you would like to donate and do not require a tax receipt, you can make a donation via Mieux Donner regardless of your country!
Charities that prioritise the final outcome of their action and not indicators of impact. When talking about impact, it is essential to focus on the desired final outcome, such as improved opportunities and quality of life, rather than focusing on intermediate outcomes such as the number of books distributed.
It’s surprising how few charities measure their impact. Our top recommended charities use scientific methods to evaluate the results of their actions, ensuring that their interventions produce the desired effects.
They save or improve the most lives per euro donated to them. Eg) our top recommended global health charities can save a life for as little as 3,000 euros, our top climate charities can avoid one ton of carbon emissions for just 1 euro and our top animal welfare charities can spare thousands of animals from factory farming for the same price of saving one animal in a refuge.
All of our top charities are independently evaluated by world leading charity evaluators. See more information below.
A life is valuable whether it is based in France or the developing world.
Our top recommended charities are all tax deductible in Switzerland, but not in France. This is because French tax law dictates that a charity must operate from France in order to be tax deductible. We always prioritise the impact of a charity over its tax deductible status.
Some of our charities such as Against Malaria Foundation have very low overhead costs, and some such as Clean Air Task Force – have much higher overhead costs. To explain why we don’t take overhead costs into account in our recommendations, imagine two charities:
In the above examples Charity A saves 1 life for every 10,000 spent on it, whereas Charity B saves 1 life for every 3,300 euros spent on it. In this example – it’s clear to see that it’s not overhead costs that are important – but in fact the ratio of overhead costs to the desired impact. Research suggests that there is not much of a correlation at all between overhead and effectiveness.
Finding the best aid organisations isn’t that easy. That’s why we work closely with experts who have been conducting extensive and in-depth research on the subject for many years. These experts are completely independent and work at the cutting edge of charity evaluation in their respective cause areas. They conduct rigorous tests on hundreds of charities to find out as precisely as possible how much good their programs achieve per euro spent. By comparing the cost effectiveness of so many charities, they are able to short list the most effective charities to donate to in order for your donations to have the biggest impact.
GiveWell is the world’s leading research organisation that studies global health and development charities.
‘We search for the charities that save or improve lives the most per dollar. Our goal is to produce the world’s top research on where to give. Free, for everyone. We recommend a small number of charities that do an incredible amount of good’ (GiveWell)
GiveWell was founded in 2007 by Holden Karnofsky and Elie Hassenfeld, two former hedge fund employees. They wanted to do as much good as possible with their donations and found that there was little solid information available on how to do this. GiveWell invests more than 40,000 hours of research each year and has raised more than €1 billion for high-impact charities, saving an estimated 150,000 lives.
The EA Animal Welfare Fund was rated as the top animal charity evaluator by GWWC’s ‘evaluating the evaluators project’ in 2024. They are therefore the primary charity evaluator we defer to in order to choose our top animal charities. We meet with them every few months to get up to date recommendations. They conduct thorough research into various animal welfare organisations to find those that help the most animals per dollar.
Giving Green is a nonprofit organisation that spends thousands of hours each year reviewing studies and climate charities to find the most cost effective interventions to combat climate change. From this research, they publish their top recommendations each year. Their team is made up of climate scientists, economists and impact evaluation experts with decades of experience working at the intersection of evidence-based policy and the environment. We meet regularly with Giving Green to discuss our climate recommendations and run climate workshops in collaboration with eachother.
Although we primarily defer to GiveWell, Giving Green and EA Animal Welfare Fund, we also read the research of other top charity evaluators including LongView Philanthropy, Founders Pledge and Animal Charity Evaluators to ensure we are not overly-reliant on any one source of research. When choosing our top charities we prefer organisations whose effectiveness is corroborated by multiple independent evaluators.
Yes, the team at Mieux Donner offers free donation advice for both english and french speakers. You can book an appointment here.
Your donation is paid directly to the organisations you support, and only transaction costs apply. Mieux Donner does not deduct any amounts for its own operations.
€8,920 collected through Mieux Donner, €746,000 in total with Effektiv Spenden: here is how the Safeguarding the Future Fund allocated its H2 2025 donations across three projects in nuclear security and AI safety.
What if the most useful donation also concerned individuals who are not yet born? Doing Good, Better: 5 Keys for More Effective Generosity We often
Discover how the OECD structures AI development to create trustworthy artificial intelligence. Analysis of AI systems, ethical principles, and capability indicators: AI has the potential to transform the world—provided it respects human rights. Explore the challenges and solutions for transparent, robust, and beneficial AI systems.
Find out how your donations can support tomorrow’s agriculture in the face of the challenges posed by the Duplomb-Menonville law: preserving competitiveness, public health and the environment.
Our “Safeguarding the Future Fund” channels donations toward the most promising initiatives aimed at reducing the greatest existential risks to humanity. It focuses on addressing threats to humanity’s long-term future such as conflicts between major powers, nuclear war, pandemics, biological weapons, catastrophic lab accidents, and emerging risks from new technologies, such as artificial intelligence (AI) and other military and civilian advancements.
